Does Cosentyx Require Delaying the Flu Shot?
No, Cosentyx (secukinumab) does not require delaying the flu shot. The inactivated influenza vaccine used in standard flu shots is safe and recommended for patients on Cosentyx, as it poses no increased infection risk from live virus.[1][2]
Why Live Vaccines Are Avoided with Cosentyx
Cosentyx suppresses the immune system by blocking IL-17, making live vaccines (like nasal flu spray or varicella) risky—they can cause infection. Inactivated vaccines like the injectable flu shot are fine year-round.[1][3]
Timing Guidelines for Flu Shot with Cosentyx
Get the flu shot anytime, even during active Cosentyx treatment. No hold period needed before or after vaccination. Studies show good immune response in patients on IL-17 inhibitors.[2][4]
What If I'm Getting Other Vaccines?
- COVID-19 or pneumococcal: Safe with Cosentyx; no delay.
- Shingles (Shingrix): Inactivated, so okay.
- Live vaccines: Avoid entirely while on Cosentyx and for 4-6 weeks after stopping.[1][3]
Patient Reports on Flu Shot Response
Some users on forums report milder or absent side effects from the flu shot while on Cosentyx, but antibody response remains protective in trials. Consult your doctor if immunocompromised further (e.g., with steroids).[4]
Official Sources and Doctor Advice
Novartis (Cosentyx maker) prescribing info confirms inactivated vaccines are safe.[1] Always check with your rheumatologist or prescriber, as individual factors like dose or comorbidities matter.
Sources
[1]: Novartis Cosentyx Prescribing Information
[2]: CDC Vaccine Guidelines for Immunocompromised
[3]: ACR Guidelines on Vaccinations in Rheumatic Diseases
[4]: Clinical Trial Data on IL-17 Inhibitors and Vaccines