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No, Cosentyx (secukinumab) does not require delaying the flu shot. The inactivated influenza vaccine used in standard flu shots is safe and recommended for patients on Cosentyx, as it poses no increased infection risk from live virus.[1][2]
Cosentyx suppresses the immune system by blocking IL-17, making live vaccines (like nasal flu spray or varicella) risky—they can cause infection. Inactivated vaccines like the injectable flu shot are fine year-round.[1][3]
Get the flu shot anytime, even during active Cosentyx treatment. No hold period needed before or after vaccination. Studies show good immune response in patients on IL-17 inhibitors.[2][4]
Some users on forums report milder or absent side effects from the flu shot while on Cosentyx, but antibody response remains protective in trials. Consult your doctor if immunocompromised further (e.g., with steroids).[4]
Novartis (Cosentyx maker) prescribing info confirms inactivated vaccines are safe.[1] Always check with your rheumatologist or prescriber, as individual factors like dose or comorbidities matter. Sources [1]: Novartis Cosentyx Prescribing Information [2]: CDC Vaccine Guidelines for Immunocompromised [3]: ACR Guidelines on Vaccinations in Rheumatic Diseases [4]: Clinical Trial Data on IL-17 Inhibitors and Vaccines
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