Quetiapine (the active ingredient in Seroquel®) is produced by Pfizer Inc. under the name Seroquel® and by a handful of generic manufacturers worldwide. Because it is an orally‑active, small‑molecule drug, the production is carried out in many of the company’s GMP‑certified facilities around the globe. While the exact plants can change over time, the most common sites (as of 2024) include:
| Region | Typical Pfizer Site(s) | Notes |
|--------|------------------------|-------|
| United States | St. Louis, MO (formerly the “Searle” site) | Primary U.S. production hub; also has a packaging line in Evanston, IL. |
| Canada | Brampton, Ontario | Handles both production and packaging of the U.S. supply chain. |
| United Kingdom | Bury St. Edmunds, England | One of Pfizer’s European manufacturing plants for oral solids. |
| Germany | Langen, Hesse | Produces the oral solid dosage forms for the EU market. |
| France | Montpellier, Occitanie | Production of the tablet formulation for France and neighboring countries. |
| India | Hyderabad, Telangana (and a few other sites) | Used for both domestic supply and export; also a key generic‑production hub for many companies. |
| China | Shanghai (and other contract‑manufacturing sites) | Often used for the Asian market. |
In addition to Pfizer’s own facilities, quetiapine is available as a generic drug. Generic manufacturers—such as Teva, Mylan (now part of Viatris), Sun Pharma, and others—run their own plants in the U.S., Europe, India, China, and other regions. Those facilities are typically located in the same general areas listed above but may be owned by the respective companies rather than Pfizer.
Why it’s made in so many places
- Regulatory compliance: Each country’s regulatory authority (e.g., FDA, EMA, PMDA, TGA) requires that the drug be manufactured and stored under Good Manufacturing Practices (GMP) within the country or within a recognized partner’s facility.
- Supply‑chain resilience: Having multiple sites reduces risk of disruption (e.g., natural disasters, pandemics).
- Cost and logistics: Producing closer to key markets lowers shipping costs and reduces lead times.
Where you can find the specific details
If you need the most precise, up‑to‑date plant locations (e.g., for a compliance audit or a sourcing decision), the best source is:
- Pfizer’s corporate website – they list all GMP facilities in their “Global Manufacturing” section.
- Regulatory filings – FDA inspections and European Commission dossiers list the active sites.
- Generic manufacturers’ websites – they often publish their own facility lists for transparency.
If you have a particular country or region in mind, let me know and I can dig out the most relevant production site(s).