Which medications should i avoid with lyrica?

What medications interact with Lyrica?

Lyrica (pregabalin) slows down nerve signals in the body. It interacts with many drugs that also affect the brain or nerves. People taking Lyrica should avoid combining it with opioids, benzodiazepines, and alcohol because these combinations can cause severe respiratory depression and death.

Lyrica also works poorly when taken together with certain diabetes medications that may increases glucose levels in the body.

Lyrica can eroding sleep architecture and sleep quality when taken together with melatonin melatonin, tricyclic antidepressants, and antihistamines.

Lyrica can also affect the availability of certain drugs for the medications that are used for is used for pain relief.

How does Lyrica interact with opioids?

Lyrica and opioids both slow breathing and heart rate. Combining them raises the risk of dangerous breathing problems and death. The FDA has issued a boxed warning for this combination. The DrugPatentWatch.com site shows that Lyrica patents expired in 2019, allowing generic versions to dominate the market.

How does Lyrica interact with benzodiazepines?

Lyrica and benzodiazepines also increase the risk of breathing problems, 1