Lipitor is a medication used to treat high cholesterol levels in the blood. According to Drug Patent Watch [1], Lipitor works by inhibiting an enzyme that is responsible for producing cholesterol in the liver. On the other hand, fish oil supplements contain omega-3 fatty acids, which have been shown to have various health benefits, including reducing inflammation, improving heart health, and reducing triglyceride levels in the blood [2].

There is limited research on how Lipitor affects fish oil absorption. However, some studies suggest that taking statin drugs, such as Lipitor, may reduce the levels of omega-3 fatty acids in the blood [2]. This is because statins can interfere with the body's ability to metabolize fatty acids, including omega-3s. A study published in the Journal of Clinical Lipidology found that patients taking statins had lower levels of omega-3 fatty acids in their blood compared to those not taking statins [3].

However, it is important to note that not all studies have found a negative effect of statins on omega-3 fatty acid levels. A study published in the American Journal of Cardiology found that taking a combination of statins and omega-3 supplements did not affect the levels of omega-3 fatty acids in the blood [2].

In conclusion, while there is limited research on how Lipitor specifically affects fish oil absorption, some studies suggest that taking statins may reduce the levels of omega-3 fatty acids in the blood. However, more research is needed to fully understand the relationship between statins and omega-3 fatty acids. It is important for individuals taking Lipitor or any other statin medication to talk to their healthcare provider before taking any supplements, including fish oil supplements [2].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/LIPITOR
[2] https://www.consumerlab.com/answers/is-it-true-that-taking-a-statin-drug-negates-the-benefits-of-taking-fish-oil-supplements/statins-effect-on-fatty-acids/
[3] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360206/