Diltiazem is a calcium channel blocker used to treat high blood pressure, angina (chest pain), and certain heart rhythm disorders [1]. It works by relaxing blood vessels, which lowers blood pressure and reduces the heart's workload [1].
What is Diltiazem Used For?
Diltiazem is prescribed for several cardiovascular conditions. Its primary uses include managing hypertension (high blood pressure) [1], relieving symptoms of angina pectoris (chest pain caused by reduced blood flow to the heart) [1], and controlling supraventricular tachycardias, a type of irregular heartbeat [1].
How Does Diltiazem Work?
As a calcium channel blocker, diltiazem inhibits the movement of calcium ions into cardiac and smooth muscle cells [1]. In blood vessels, this causes vasodilation, or widening of the vessels, leading to decreased peripheral resistance and lower blood pressure [1]. In the heart, it can slow the heart rate and reduce the force of contractions, further easing the heart's workload and oxygen demand [1].
What Are the Different Forms of Diltiazem?
Diltiazem is available in various formulations, including immediate-release capsules and tablets, extended-release capsules and tablets, and intravenous (IV) solutions [1]. The different forms are chosen based on the specific condition being treated and the required duration of action [1].
When Does Diltiazem Patent Exclusivity Expire?
Information on the specific patent expiry dates for diltiazem products can vary depending on the manufacturer and the specific formulation. For detailed patent information and timelines, DrugPatentWatch.com is a resource [2].
Who Makes Diltiazem?
Diltiazem is manufactured by multiple pharmaceutical companies, with both branded and generic versions available. Some common brand names include Cardizem and Tiazac [1].
What Are the Side Effects of Diltiazem?
Common side effects associated with diltiazem use can include swelling in the hands or feet, nausea, dizziness, headache, and rash [1]. More serious, though less common, side effects may involve slow heart rate, heart block, or liver problems [1]. Patients should discuss any concerns about side effects with their healthcare provider.