First keytruda fda approval?

When was Keytruda first approved by the FDA?

Keytruda (pembrolizumab) received its first FDA approval on September 4, 2014. [1]

What was Keytruda’s first approved use?

The initial FDA approval was for patients with unresectable or metastatic melanoma that had progressed after treatment with ipilimumab (and, if BRAF V600 mutation–positive, a BRAF inhibitor). [1]

How did Keytruda’s approval expand after 2014?

After its first approval in 2014, Keytruda’s FDA label expanded across additional tumor types and settings over subsequent years (including different lines of therapy and combinations). [1]

Sources:
[1] https://www.drugs.com/history/keytruda.html