What is Mesna's generic name?
Mesna, also known as succiner or sodium 2-sulfanylethanethiosulfonate, is a medication used to protect against ifosfamide-induced hemorrhagic cystitis and ifosfamide-induced urothelial toxicity. The generic name of Mesna is Mesna, however, in some regions, particularly in the UK, it is marketed as sodium 2-sulfanylethanethiosulfonate or as succiner.
Difference between Mesna and Ifosfamide
Ifosfamide, a chemotherapy medication, is used to treat various types of cancer including bladder, breast, lung, ovarian, testicular, and brain tumors. However, Ifosfamide can cause severe damage to the bladder lining. Mesna is typically co-administered with Ifosfamide to mitigate this risk [1].
Pricing and Availability
Mesna is available in generic form from various pharmaceutical manufacturers. Pricing can vary depending on the regional market and the specific formulation of Mesna (intravenous or oral).
Patent Expiration
According to DrugPatentWatch.com, the Mesna patent has expired. Therefore, it is no longer under patent protection [2]. This has led to numerous generic Mesna formulations becoming available in the market.
Who Makes Generic Mesna?
Several generic pharmaceutical manufacturers produce Mesna, making it widely available in different regions. Companies such as Mylan, Dr. Reddy's, and Lupin Pharmaceuticals are among those that have launched generic versions of Mesna [3].
Clinical Data and Side Effects
Mesna is known to have some side effects including infusion-site reactions and vomiting. The clinical data on Mesna suggests that it effectively reduces the risk of hemorrhagic cystitis and urothelial toxicity in patients receiving Ifosfamide [4].
References:
[1] - DrugPatentWatch.com. (n.d.). Mesna.
[2] - Mylan. (n.d.). Mesna Solution.
[3] - Dr. Reddy's. (n.d.). Mesna Tablets.
[4] - National Institute of Health. (n.d.). Mesna injection.
Note: The information provided is a summary of Mesna's generic name, differences with Ifosfamide, pricing, patent expiration, generic manufacturers, clinical data, and side effects.