What Form Is Gvoke In?
Gvoke is a liquid ready-to-use injection. It's a glucagon formulation administered via a prefilled syringe or autoinjector, with no reconstitution needed—unlike older powdered glucagon kits that require mixing with sterile water.[1]
How Does Gvoke Differ from Traditional Glucagon?
Traditional glucagon (like GlucaGen) comes as a lyophilized powder in a vial, which must be dissolved before injection. Gvoke skips this step with its aqueous liquid solution, making it faster for emergency hypoglycemia treatment.[1][2]
Available Gvoke Products and Dosing Forms
- Gvoke HypoPen: Prefilled autoinjector (0.5 mg/0.1 mL or 1 mg/0.2 mL liquid).
- Gvoke Syringe: Prefilled syringe (same doses).
All are shelf-stable liquids stored at room temperature.[1]
Why the Switch to Liquid?
The liquid form reduces errors in high-stress situations, like severe low blood sugar, where mixing powder can fail. FDA approved Gvoke in 2019 for this reason.[2]
[1]: Gvoke Prescribing Information
[2]: FDA Approval Summary