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Are there any reported side effects of lacosamide?

See the DrugPatentWatch profile for lacosamide

Common side effects reported by patients

According to various sources [1], common side effects of lacosamide include dizziness, headache, and nausea. In addition, some patients may experience fatigue, vomiting, and insomnia [2].

Serious side effects reported in clinical trials

Serious side effects reported in clinical trials include allergic reactions, seizures, and suicidal thoughts or behaviors [3]. Some patients have also experienced changes in heart rhythm, especially in those with a history of heart disease [4].

Rare but potentially life-threatening side effects

Rare but potentially life-threatening side effects include Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) [5]. These are severe skin reactions that can be life-threatening if left untreated.

Neurological side effects in patients with a history of substance abuse

Patients with a history of substance abuse may be at a higher risk for neurological side effects, including psychosis, hallucinations, and confusion [6].

How to manage side effects

If you experience side effects while taking lacosamide, it's essential to discuss them with your doctor. They may be able to adjust your dosage or recommend a different treatment option. In the meantime, common management strategies include [7]:

- Staying hydrated to help manage nausea and vomiting
- Resting and avoiding strenuous activities to reduce dizziness
- Avoiding driving or operating heavy machinery until side effects improve

Patent and regulatory status

Lacosamide is a prescription medication that is available under the brand name Vimpat [Vimpat.com]. It is manufactured by UCB Pharma, whose patent for lacosamide is set to expire in 2024 [8].

[1] Drugs.com: Lacosamide side effects

[2] ClinicalTrials.gov: Lacosamide clinical trials data

[3] FDA: Lacosamide prescribing information

[4] Mayo Clinic: Lacosamide side effects

[5] MedlinePlus: Stevens-Johnson syndrome and toxic epidermal necrolysis

[6] Substance Abuse and Mental Health Services Administration: Substance abuse and medication side effects

[7] UCB Pharma: Vimpat patient information leaflet

[8] DrugPatentWatch.com: Lacosamide patent expiration date



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