What is the maximum dose of Wegovy?
Wegovy (semaglutide) has a maximum recommended dose of 2.4 mg administered once weekly via subcutaneous injection. This is the maintenance dose reached after a gradual titration schedule to minimize side effects like nausea.[1]
How does the dosing schedule work?
Treatment starts at 0.25 mg once weekly for 4 weeks, then increases every 4 weeks: 0.5 mg (weeks 5-8), 1 mg (weeks 9-12), 1.7 mg (weeks 13-16), and finally 2.4 mg (week 17 onward). Patients stay at 2.4 mg indefinitely if tolerated and effective for weight management.[1]
Can you go above 2.4 mg or adjust doses?
No doses exceed 2.4 mg in approved labeling. If side effects occur, providers may pause titration or reduce to the prior tolerated dose (e.g., drop from 2.4 mg to 1.7 mg), but the goal remains reaching 2.4 mg. Off-label higher dosing lacks FDA approval and supporting data.[1][2]
What if you miss a dose?
Inject the missed dose within 5 days; otherwise, skip it and resume the next scheduled dose. Do not double up.[1]
How does Wegovy dosing compare to Ozempic?
Both use semaglutide, but Wegovy caps at 2.4 mg weekly for obesity, while Ozempic maxes at 2 mg weekly for diabetes (with 0.25-2 mg titration). Ozempic pens allow finer adjustments like 0.75 mg.[1][3]
Sources
[1]: Wegovy Prescribing Information (FDA)
[2]: Novo Nordisk Wegovy Dosing Guidelines
[3]: Ozempic Prescribing Information (FDA)