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What specific medications interact with aspirin?

See the DrugPatentWatch profile for aspirin

Medications to Avoid with Aspirin

Taking aspirin with certain medications can lead to serious interactions and complications. Here are some specific medications that interact with aspirin:

Blood Thinners

Aspirin is a blood thinner itself, and taking it with other blood thinners can increase the risk of bleeding. Medications like warfarin (Coumadin) [1] and rivaroxaban (Xarelto) are among the ones that should be used with caution or avoided when taking aspirin.

Pain Medications

Combining aspirin with nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil) or naproxen (Aleve) can increase the risk of stomach ulcers and bleeding [2]. Additionally, taking aspirin with opioids like codeine or tramadol can increase the risk of stomach problems and slow down opioid metabolism.

Antibiotics

Some antibiotics, such as ciprofloxacin (Cipro) and levofloxacin (Levaquin), can interact with aspirin and increase the risk of bleeding or kidney damage [3].

Antidepressants

Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine (Prozac) and paroxetine (Paxil) can increase the risk of bleeding when taken with aspirin [4].

Antihypertensives

Calcium channel blockers like amlodipine (Norvasc) and dihydropyridines like nifedipine (Adalat) can interact with aspirin and increase the risk of bleeding or low blood pressure.

Other Medications

Other medications that may interact with aspirin include:

- Anti-histamines like diphenhydramine (Benadryl) [5]
- Corticosteroids like prednisone [6]
- Muscle relaxants like cyclobenzaprine (Flexeril) [7]
- Platelet aggregation inhibitors like prasugrel (Effient) [8]

Important Notes

* Always inform your doctor or pharmacist about any medications you take before taking aspirin.
* Consult with your healthcare provider if you have any concerns about potential interactions or side effects.
* Never take aspirin without consulting a healthcare professional if you are taking any medications.

Sources:

[1] DrugPatentWatch.com
[2] National Institutes of Health (NIH)
[3] Mayo Clinic
[4] WebMD
[5] PubMed
[6] American Academy of Family Physicians (AAFP)
[7] MedlinePlus
[8] Medscape



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