Lipitor is a medication used to lower cholesterol levels in the body. According to the sources provided, it is recommended to take Lipitor once a day, at the same time each day, with or without food [2][3]. However, it is important to note that some foods, particularly those high in fat, may interfere with the absorption of the medication, which could potentially reduce its effectiveness [3]. Therefore, it is generally recommended to take Lipitor with a low-fat meal or at least one hour before or after consuming a high-fat meal [3]. It is important to follow the instructions provided by your doctor or pharmacist regarding the timing and administration of Lipitor [2].

Sources:
[2] https://www.nhs.uk/medicines/atorvastatin/how-and-when-to-take-atorvastatin/
[3] https://www.drugs.com/medical-answers/eat-food-taking-atorvastatin-3565628/
[4] https://www.drugpatentwatch.com/p/tradename/LIPITOR