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Is lyrica considered a banned substance in professional sports?

See the DrugPatentWatch profile for lyrica

Is Lyrica Banned in Professional Sports?


No, Lyrica (pregabalin) is not a banned substance in professional sports. It's permitted for therapeutic use with a Therapeutic Use Exemption (TUE) in organizations like the World Anti-Doping Agency (WADA), USADA, and IOC. Athletes must apply for TUE approval if using it for conditions like neuropathic pain or fibromyalgia, as it's monitored on WADA's Prohibited List under S4 (Hormones and Modulators) or as a potential masking agent, but not outright banned.[1][2]

Why Is Pregabalin Monitored but Not Fully Prohibited?


Pregabalin appears on WADA's 2024 Monitoring Program, tracking its use without automatic sanctions. This allows detection of potential abuse patterns, like masking other drugs' effects or performance enhancement claims (unsubstantiated). It's not listed as prohibited in- or out-of-competition on the core 2024 WADA Prohibited List.[3]

What Sports Organizations Regulate It?


- WADA/IOC: Requires TUE for approved medical use; no ban otherwise.
- UFC/USADA: Pregabalin permitted with TUE; flagged in past tests (e.g., Jon Jones 2016 case dismissed after TUE review).[4]
- NFL/NBA/MLB: Follow WADA-aligned rules via their programs; no blanket ban.
- Cycling (UCI): Similar TUE process; occasional detections but no automatic positives.

How Do Athletes Get Approval for Lyrica?


Submit TUE at least 30 days pre-competition (or retroactively in emergencies) via ADAMS platform, including diagnosis, dosage, and alternatives tried. Approval lasts up to 2 years, renewable. Without TUE, a positive test risks sanctions.[1][5]

Has Pregabalin Caused Doping Violations?


Rarely leads to bans when TUE-presented. Notable cases:
- Jon Jones (UFC, 2016/2017): Traces found, but cleared via TUE/arbitration.
- No major widespread scandals; detections often <1% of tests.[4][6]

Alternatives for Athletes with Pain Conditions?


Gabapentin (similar to pregabalin, also TUE-required), NSAIDs (ibuprofen, permitted without TUE unless specified), or acetaminophen. Non-drug options like PT prioritized in TUE denials.[2]

[1]: WADA 2024 Prohibited List
[2]: USADA TUE Guidelines
[3]: WADA Monitoring Program 2024
[4]: USADA Jon Jones Case
[5]: Global DRO TUE Info
[6]: WADA Testing Figures 2023



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