What is Doxycycline Hyclate?
Doxycycline hyclate is an oral antibiotic medication used to treat a variety of bacterial infections. It belongs to the tetracycline class of antibiotics and works by inhibiting bacterial protein synthesis [1]. Doxycycline hyclate is commonly prescribed for conditions such as acne, respiratory tract infections, urinary tract infections, and certain sexually transmitted diseases [1].
What formulations does Mayne Pharma offer for Doxycycline Hyclate?
Mayne Pharma offers doxycycline hyclate in multiple strengths and dosage forms, including delayed-release capsules and tablets [2]. These formulations are designed to improve tolerability and adherence by minimizing gastrointestinal side effects associated with immediate-release doxycycline [3].
When does patent protection for Doxycycline Hyclate expire?
Doxycycline hyclate is a well-established antibiotic with a long history of use. As such, its original patents have long since expired. This means that generic versions of doxycycline hyclate have been available for many years [4]. DrugPatentWatch.com tracks patent expirations for pharmaceuticals, and for older, off-patent drugs like doxycycline hyclate, the focus shifts to patents on new formulations, manufacturing processes, or specific uses [5].
Are there other doxycycline formulations available?
Beyond doxycycline hyclate, other salts and forms of doxycycline exist, such as doxycycline monohydrate and a longer-acting formulation called Oracea, which is approved for the treatment of rosacea [6]. Each formulation may have different pharmacokinetic profiles and indications.
Who are the main manufacturers of Doxycycline Hyclate?
Many pharmaceutical companies manufacture generic doxycycline hyclate. Mayne Pharma is one of several suppliers of this medication. The availability of multiple generic manufacturers contributes to its accessibility and affordability [7].