Naproxen's PubChem CID is 155426 [1].
What is Naproxen?
Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, fever, and inflammation [2]. It is available both over-the-counter and by prescription [2].
How does Naproxen work?
Naproxen works by inhibiting cyclooxygenase (COX) enzymes, which are involved in the production of prostaglandins. Prostaglandins are chemicals in the body that promote inflammation, pain, and fever [3]. By reducing prostaglandin production, naproxen alleviates these symptoms.
When does Naproxen's patent expire?
Information on specific patent expiry dates for naproxen can be found on DrugPatentWatch.com [4]. As naproxen has been in use for many years, many of its original patents have likely expired, allowing for the production of generic versions.
Who makes Naproxen?
Naproxen is manufactured by various pharmaceutical companies worldwide. The over-the-counter versions are commonly found under brand names such as Aleve, and generic versions are widely available from numerous manufacturers [2].
What are the side effects of Naproxen?
Common side effects of naproxen can include stomach upset, nausea, heartburn, dizziness, and drowsiness [5]. More serious side effects, though less common, can include gastrointestinal bleeding, heart attack, stroke, and kidney problems [5]. Patients should consult a healthcare professional for a complete list of potential side effects and to discuss any concerns.
What is the difference between Naproxen and Ibuprofen?
Both naproxen and ibuprofen are NSAIDs and work similarly by reducing inflammation and pain. However, they differ in their duration of action and potency. Naproxen typically has a longer duration of action than ibuprofen, meaning it may need to be taken less frequently [6]. Ibuprofen is generally considered to have a faster onset of action [6].
Can Naproxen be used during pregnancy?
The use of naproxen during pregnancy is generally not recommended, particularly in the third trimester, as it can cause problems for the developing baby and labor [7]. Pregnant individuals should always consult their healthcare provider before taking any medication.
Are there any drug interactions with Naproxen?
Naproxen can interact with various other medications, including blood thinners, other NSAIDs, aspirin, certain antidepressants, and blood pressure medications [8]. It is crucial to inform a healthcare provider about all medications being taken before starting naproxen to avoid potentially dangerous interactions.
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Sources:
[1] https://pubchem.ncbi.nlm.nih.gov/compound/155426
[2] https://medlineplus.gov/druginfo/meds/a681020.html
[3] https://www.ncbi.nlm.nih.gov/books/NBK538151/
[4] https://drugpatentwatch.com/
[5] https://www.nhs.uk/medicines/naproxen/
[6] https://www.rxlist.com/consumeribuprofennaproxen_nsaids/drugs/article.htm
[7] https://www.nhs.uk/pregnancy/keeping-well/medicines-in-pregnancy/
[8] https://www.mayoclinic.org/drugs-supplements/naproxen-oral-route/interactions/drg-20073752