A shortage of Linzess (linaclotide), a medication used to treat irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC), has been reported [1]. This shortage impacts the availability of the drug for patients relying on it for symptom management [2].
What is causing the Linzess shortage?
The specific reasons for the Linzess shortage are not publicly detailed by the manufacturer. However, drug shortages can stem from various factors, including manufacturing disruptions, supply chain issues, increased demand, or raw material scarcity [3]. These challenges can affect the production and distribution of necessary medications.
How long might the Linzess shortage last?
Information regarding the expected duration of the Linzess shortage is not readily available. Manufacturers typically provide updates on their websites or through regulatory channels when they have a clearer timeline for resolution [3]. Patients experiencing difficulty obtaining their medication should consult with their healthcare provider.
What can I do if I can't find Linzess?
If you are unable to locate Linzess, it is recommended to speak with your prescribing doctor or a pharmacist [4]. They can offer guidance on potential alternative treatments that may be suitable for your condition. It may also be helpful to check with multiple pharmacies, as inventory levels can vary.
What are alternatives to Linzess for constipation?
Several alternative medications and strategies exist for managing constipation associated with IBS-C and CIC. These may include other prescription medications like lubiprostone (Amitiza) or plecanatide (Trulance), which work similarly to linaclotide by increasing fluid secretion in the intestines [5][6]. Over-the-counter options, such as fiber supplements, osmotic laxatives (e.g., polyethylene glycol), or stimulant laxatives, might also be recommended by a healthcare provider, depending on the individual's specific needs and medical history [7]. Lifestyle changes, including increased fluid intake and dietary adjustments, are also important components of constipation management [8].
Who manufactures Linzess?
Linzess is manufactured by Ironwood Pharmaceuticals in collaboration with AbbVie [9].
Sources:
1. https://www.drugpatentwatch.com/news/drug-shortage-updates/linzess-shortage-reported
2. https://www.drugpatentwatch.com/drugs/linzess
3. https://www.fda.gov/drugs/drug-shortages/drug-shortages-faqs
4. https://www.goodrx.com/linzess
5. https://www.trulance.com/
6. https://www.amitiza.com/
7. https://www.mayoclinic.org/diseases-conditions/constipation/diagnosis-treatment/drc-20354244
8. https://www.iffgd.org/assets/documents/GastrointestinalConditions/IBS-CPatient_Guide.pdf
9. https://www.ironwoodpharma.com/our-business/