Mesalamine is the generic name for the drug used to treat ulcerative colitis, Crohn’s disease, and other inflammatory bowel conditions. In many countries the drug is also called mesalazine (especially in Europe and Asia), but the active ingredient is the same.
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Common brand names (in the U.S. and many other countries)
| Brand (U.S.) | Brand (Europe/Canada/Other) | Form & Typical Dose |
|--------------|----------------------------|---------------------|
| Asacol® | Asacol® | Delayed‑release tablets (2.25 mg, 4.5 mg, 9 mg) – usually 4–6 tablets per day |
| Lialda® | Lialda® | Delayed‑release tablets (2 mg, 4 mg, 8 mg) – often 2–3 tablets per day |
| Pentasa® | Pentasa® | Immediate‑release tablets (50 mg, 100 mg, 200 mg, 300 mg) – 2–3 tablets per day |
| Apriso® | Apriso® | Delayed‑release tablets (2 mg, 4 mg, 8 mg) – 2–3 tablets per day |
| Entocort® | Entocort® | Suppositories & enemas – used for proctitis and distal colitis |
| Lodine® | Lodine® | Suppositories & enemas – for proctitis |
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How it works
Mesalamine is an anti‑inflammatory agent that acts locally in the colon (and rectum, when given rectally). It is not absorbed systemically in large amounts, which limits systemic side effects.
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When a “generic” is available
- Generic mesalamine is usually sold in the same tablet, capsule, or rectal form as the branded products, often at a lower cost.
- In the U.S., the generic can be found under the name mesalamine (often marketed as “mesalamine tablets” or “mesalamine delayed‑release tablets”).
- In the U.K. and many European countries, the generic is sold as mesalazine.
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Quick Tips
| Situation | Recommendation |
|-----------|----------------|
| Looking for a lower‑price option | Buy generic mesalamine; confirm the dosage match with your prescriber. |
| Need rectal treatment | Ask for mesalamine suppositories/enemas (Entocort or Lodine). |
| Side‑effects or intolerance | Talk to your doctor about switching formulation (e.g., delayed vs. immediate release). |
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If you’re unsure which specific formulation or brand is right for you, check the prescription label or ask your pharmacist or gastroenterologist. They can match the generic or brand to your exact dosing schedule and symptom profile.