Emgality?

Emgality is the brand name for galcanezumab. It’s a prescription monoclonal antibody that targets CGRP (calcitonin gene–related peptide), a molecule involved in migraine and cluster headache pathways.

What it’s used for
- Prevention of migraine in adults (monthly injections).
- Prevention of episodic cluster headache in adults.

How it’s given
- Subcutaneous injections, usually once a month.
- For migraine prevention, the typical schedule starts with a loading period (often two 120 mg injections to total 240 mg) followed by 120 mg monthly.
- For episodic cluster headache prevention, a monthly dose is given (the exact amount should be per your doctor’s guidance and the label).

How soon you might notice an effect
- It can take several weeks to see benefit. It’s a preventive therapy, not an acute treatment for headaches.

Common side effects
- Injection-site reactions (redness, pain, or swelling)
- Constipation
- Other possible effects: upper respiratory infections, back pain, dizziness

Important cautions
- Not for acute treatment of a migraine attack.
- Not a cure; you’ll need ongoing injections to maintain benefit.
- If you have a severe allergic reaction (rash, swelling of face/throat, trouble breathing), seek urgent care.
- If you’re pregnant, trying to become pregnant, or breastfeeding, talk with your doctor about risks and alternatives.
- Discuss with your clinician about other medicines you take, including other migraine preventives.

If you’d like, tell me what you want to know more specifically (how it works, exact dosing for migraine vs cluster, potential side effects, cost/coverage, or how to use the injections), and I’ll tailor the details.