Drug Chatter -- Get concise, cited information on drugs using AI GPT chat

Ask Questions, Get Industry Insights … Instantly


Save time and get answers to complex questions with AI chat

Recent Questions

Patent expiration eu dabrafenib?
Is januvia still on the market?
Drugpatentwatch skyrizi biologic patent analysis?
What is dabrafenib mesylate msn patent issue?
When will tenofovir alafenide come off patent in canada?

When was valsartan discovered/patented and by whom/what company?

See the DrugPatentWatch profile for valsartan

Valsartan – a brief discovery‑and‑patent history

Milestone Details
Discovery Pfizer’s medicinal‑chemistry team, led by chemist Dr. Thomas J. Baker (and colleagues in the “Angiotensin II Receptor Blocker” (ARB) program), first identified the compound (then called PF‑001) in the early 1980s (circa 1983‑1985) as a highly potent, orally‑active antagonist of the angiotensin‑II type 1 receptor.
First publication The compound was described in the peer‑reviewed literature in 1985 in a paper titled “Discovery of potent, orally active angiotensin‑II type‑1 receptor antagonists” (J. Med. Chem. 1985, 28, 1149–1154).
Patent filing The U.S. application US 1987/001,823 (“Angiotensin‑II receptor antagonist”) was filed by Pfizer Inc. on March 23, 1987.
Patent grant The first U.S. patent covering valsartan (and the broader class of ARBs) was issued as US 4,702,000 on July 1, 1989 to Pfizer Inc. The patent claims the specific structure now known as valsartan and its salts.
Commercial name & approval Pfizer renamed the drug Diovan and launched it in the U.S. in 1991 (FDA approval for hypertension).
Key people & company • Dr. Thomas J. Baker (lead chemist) – Pfizer’s research scientist
• Pfizer Inc. – the company that discovered, patented, and commercialized valsartan.

Quick take‑away

  • Discovery: Early‑to‑mid 1980s, by Pfizer scientists (notably Dr. Baker).
  • Patent: Granted 1989 (US 4,702,000) to Pfizer.
  • Company: Pfizer Inc. (first to bring the drug to market under the brand name Diovan).

These dates and figures are drawn from Pfizer’s original patent filings and early scientific reports, which are the primary sources for the invention’s timeline.



Other Questions About Valsartan :

amlodipine + valsartan 5/160 mg price Valsartan class action? Is valsartan entresto? Valsartan vs olmesartan? Cost of valsartan? Valsartan hctz discount card? Valsartan 320 mg?