Advil, also known as ibuprofen, is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. It is important to note that NSAIDs, including Advil, can irritate the lining of the stomach and cause acid reflux symptoms [2]. Therefore, it is generally not recommended to take Advil with other acid reflux medications without consulting a healthcare provider.

According to Drug Patent Watch [1], there are no known drug interactions between Advil and acid reflux medications such as proton pump inhibitors (PPIs) and H2 blockers. However, it is important to note that taking Advil and other NSAIDs with PPIs or H2 blockers may increase the risk of stomach bleeding and ulcers [2]. Therefore, it is important to talk to a healthcare provider before taking Advil with any acid reflux medication.

The Mayo Clinic [2] recommends avoiding NSAIDs, including Advil, if you have GERD (gastroesophageal reflux disease) or frequent heartburn. They suggest using acetaminophen instead, as it is less likely to irritate the stomach lining and cause acid reflux symptoms.

If you do need to take Advil for pain relief and also take an acid reflux medication, it is important to take the medications as directed and not exceed the recommended dosage. Additionally, it is important to talk to a healthcare provider before taking any new medications, including over-the-counter medications like Advil [3].

In conclusion, while there are no known drug interactions between Advil and acid reflux medications, it is generally not recommended to take them together without consulting a healthcare provider. It is important to consider the potential risks and benefits and talk to a healthcare provider before taking any new medications [1][2][3].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://www.mayoclinic.org/diseases-conditions/gerd/expert-answers/heartburn-gerd/faq-20058535
[3] https://medlineplus.gov/ency/patientinstructions/000197.htm