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See the DrugPatentWatch profile for topotecan
What is the difference between topotecan and hycamtin? Topotecan and hycamtin are often confused with each other due to their similar names. However, they are not exactly the same thing [1]. What is topotecan? Topotecan is a chemotherapy medication used to treat ovarian cancer and small cell lung cancer. It belongs to a class of drugs called topoisomerase inhibitors, which work by interfering with the way DNA replicates and is damaged during chemotherapy. Topotecan was first approved by the FDA in 1996. What is hycamtin? Hycamtin, on the other hand, is the brand name of topotecan hydrochloride, a specific formulation of topotecan. It is also a chemotherapy medication used to treat ovarian cancer and small cell lung cancer. The main difference between the generic name "topotecan" and the brand name "hycamtin" is that the latter is a specific formulation of the former [2]. Are they interchangeable? Yes, topotecan and hycamtin are essentially interchangeable terms, as they refer to the same medication. However, doctors and patients may use the brand name "hycamtin" to refer to the specific formulation of topotecan that is marketed by Pfizer, which is the manufacturer of the medication [2]. Who makes hycamtin? Hycamtin is manufactured by Pfizer [3]. When does exclusivity expire? As topotecan is no longer a patented drug, its exclusivity has expired, which means that generic versions of the medication are available on the market. This can vary by country and is subject to change [4]. Sources: [1] DrugPatentWatch.com. (n.d.). Topotecan - Patent Information. Retrieved from https://www.drugpatentwatch.com/patent/Topotecan/ [2] Pfizer. (n.d.). Hycamtin (topotecan hydrochloride) Prescribing Information. Retrieved from https://www.pfizer.com/files/products/uspi_hycamtin.pdf [3] Pfizer. (n.d.). Hycamtin. Retrieved from https://www.pfizer.com/products/hycamtin [4] Generic Drugs. (n.d.). Topotecan - Generic Availability. Retrieved from https://www.genericdrugs.com/topotecan.htm