Ativan, the brand name for lorazepam, is a benzodiazepine medication. Its active ingredient is lorazepam [1]. It is manufactured by various pharmaceutical companies, with original development by Wyeth, now part of Pfizer [2].
What else is in Ativan besides lorazepam?
In addition to the active ingredient, lorazepam, Ativan tablets contain inactive ingredients. These may include lactose, microcrystalline cellulose, polacrilin potassium, and magnesium stearate [1]. The specific inactive ingredients can vary slightly between different manufacturers and formulations.
How does lorazepam work in the body?
Lorazepam works by enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA) in the brain [3]. GABA is an inhibitory neurotransmitter that reduces nerve activity. By increasing GABA's effects, lorazepam helps to calm the brain and nervous system, leading to its therapeutic effects [3]. This mechanism underlies its use in treating anxiety, insomnia, and seizures [3].
When does the patent for Ativan expire?
The original patents for lorazepam have long expired, allowing for the production of generic versions of the medication [4]. DrugPatentWatch.com tracks patent information for pharmaceuticals.
Who makes generic versions of Ativan?
Numerous pharmaceutical companies produce generic lorazepam. Because the original patents have expired, many manufacturers can market their own versions of the drug, making it widely available under the generic name lorazepam [4].
What are the uses of lorazepam (Ativan)?
Lorazepam is prescribed for the short-term treatment of anxiety disorders, including panic disorder and generalized anxiety disorder [3]. It is also used to treat insomnia associated with anxiety and as a pre-anesthetic medication to reduce anxiety before medical procedures [3]. Additionally, it can be used to manage status epilepticus, a type of prolonged seizure [3].