Advil is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce fever [2]. It contains ibuprofen, which works by blocking the production of prostaglandins, which are responsible for causing pain, inflammation, and fever [3]. However, NSAIDs like Advil can cause stomach issues such as ulcers, bleeding, and perforation [2].

According to MedlinePlus, taking Advil with food or milk can help prevent stomach upset [2]. This is because food or milk can help coat the stomach and protect it from the irritation that Advil may cause. It is also recommended to take Advil with a full glass of water to help prevent stomach issues [2].

However, it is important to note that taking Advil with food may delay the onset of pain relief [1]. This is because the food may slow down the absorption of the medication into the bloodstream, which can delay its effects [1]. Therefore, it is recommended to take Advil on an empty stomach if immediate pain relief is needed [1].

In summary, taking Advil with food or milk can help prevent stomach upset, but it may also delay the onset of pain relief. It is important to follow the recommended dosage and to talk to a healthcare provider if any stomach issues occur while taking Advil [2].

Sources:
[1] https://www.drugpatentwatch.com/p/tradename/ADVIL
[2] https://medlineplus.gov/druginfo/meds/a682159.html
[3] https://www.ncbi.nlm.nih.gov/books/NBK310269/