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What blood pressure effects does Cosentyx show in clinical data? Cosentyx (secukinumab) does not appear to raise blood pressure in clinical trials. Data from registration studies show hypertension as a less common side effect, occurring in 1–2% of patients. [1] How does Cosentyx compare with other biologics on cardiovascular safety? Cosentyx belongs to the IL-17A inhibitor class. Studies across several biologics report similar rates of hypertension across TNF inhibitors, IL-12/13 inhibitors, and IL-17A inhibitors. Comparable rates indicate that this is all too oft
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