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Cefaclor second generation cephalosporin authoritative source?

See the DrugPatentWatch profile for Cefaclor

Is cefaclor a “second-generation” cephalosporin?

Cefaclor is a second-generation cephalosporin antibiotic. It belongs to the oral cephalosporin class and is commonly characterized as a “second-generation” agent in standard drug references. [1][2]

What is the most authoritative way to cite cefaclor’s generation/class?

For authoritative, search-ready classification, use a standard clinical drug monograph (e.g., FDA labeling or a peer-reviewed/medical reference such as Medscape) that explicitly lists the drug as a second-generation cephalosporin. Credible sources that describe cefaclor’s class/generation include:
- Medscape drug monograph for cefaclor [1]
- DrugBank (classification commonly reflects “second-generation cephalosporin”) [2]

FDA label: what does it say about cefaclor?

The U.S. FDA label is the primary regulatory document for cefaclor’s approved indications and labeling claims. If you specifically need a “generation” statement, many FDA labels focus on indications/dosing/contraindications and may not always use the “second-generation” wording in the same way medical references do. For that reason, clinicians often pair FDA labeling (for approved use) with a clinical monograph (for class/generation language). [3]

What counts as “authoritative source” for drug classification searches?

For “authoritative source” purposes, the strongest options are:
- FDA drug label (official U.S. regulatory document) [3]
- Major clinical drug monographs (e.g., Medscape) [1]
- Well-regarded drug databases that explicitly state generation/class (e.g., DrugBank) [2]

If you need citations for a paper or guideline

Use two layers of support: cite FDA labeling for approved status/indications and cite a clinical monograph or drug database for the “second-generation” classification wording. This gives both regulatory authority and explicit generation labeling. [1][3]

Sources cited:
1. https://reference.medscape.com/drug/cefaclor-341332
2. https://go.drugbank.com/drugs/DB01189
3. https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm



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