Dutasteride is manufactured by GlaxoSmithKline [1]. The drug is marketed under the brand name Avodart [2].
What is Avodart used for?
Avodart is prescribed to treat symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate [2]. It is also used in combination with the medication tamsulosin to treat moderate to severe symptoms of BPH [2].
How does dutasteride work?
Dutasteride belongs to a class of drugs known as 5-alpha reductase inhibitors [3]. It works by reducing the amount of dihydrotestosterone (DHT) in the body. DHT is a hormone that contributes to prostate growth [2]. By lowering DHT levels, dutasteride helps to shrink the prostate and improve urinary flow [2].
When does the patent for Avodart expire?
Patent expiry dates for medications like Avodart can vary by region and may be subject to legal challenges. Information on specific patent expiries can be found through resources that track drug patents, such as DrugPatentWatch.com [4].
Are there generic versions of Avodart available?
As patents expire, generic versions of medications often become available, potentially offering a lower-cost alternative. The availability of generic dutasteride depends on the patent status in specific markets [4].
What are the side effects of dutasteride?
Common side effects of dutasteride include decreased libido, erectile dysfunction, and ejaculation disorders [2]. Less common side effects may also occur [2]. Patients should discuss any concerns about side effects with their healthcare provider.
How does dutasteride compare to other BPH treatments?
Dutasteride is a 5-alpha reductase inhibitor. Other classes of drugs used to treat BPH include alpha-blockers, which relax muscles in the prostate and bladder neck to improve urine flow. Some treatments may combine these different mechanisms of action for enhanced effectiveness [2].