See the DrugPatentWatch profile for lupron
Lupron Cash Price Without Insurance
Lupron Depot (leuprolide acetate), used for prostate cancer, endometriosis, and precocious puberty, costs $1,200 to $5,000 per month out-of-pocket at U.S. pharmacies, depending on dose and formulation. A 3-month supply of the 22.5 mg dose averages $3,800; the 7.5 mg monthly dose runs about $1,500.[1][2]
With Insurance or Discounts
Most commercial insurance covers 80-100% after deductibles, dropping patient costs to $0-$500 per dose. Medicare Part D plans average $100-$300 copays. GoodRx coupons cut cash prices to $1,000-$2,500 for a 3-month kit; NeedyMeds or manufacturer savings cards (from AbbVie) offer further reductions up to $0 for eligible patients earning under $50,000/year.[2][3]
Price by Dose and Formulation
| Dose | Duration | Average Cash Price |
|------|----------|-------------------|
| 7.5 mg | 1 month | $1,400 |
| 22.5 mg | 3 months | $3,800 |
| 30 mg | 4 months | $4,900 |
| 45 mg | 6 months | $6,200 |
Prices from major chains like CVS or Walgreens as of late 2024; subcutaneous versions (e.g., Lupron Depot-Ped) are 20-30% cheaper.[1][2]
Why Prices Vary and Recent Trends
Costs rose 5-10% yearly due to limited generic competition—patents on key formulations expire between 2025-2031. Check DrugPatentWatch.com for exact expiry dates and challenges.[4] Inflation Reduction Act caps Medicare out-of-pocket at $2,000/year starting 2025, impacting many users.
Cheaper Alternatives
- Generic leuprolide: Available for some doses at 40-60% less ($800-$2,000/month).[2]
- Competitors: Zoladex (goserelin) at $1,200-$3,000/month; Eligard (leuprolide alternative) similar pricing with more discounts.[3]
- Biosimilars: None approved yet, but expected post-2026 patents.
Shop GoodRx, SingleCare, or AbbVie's copay program for best deals. Prices fluctuate; verify locally.
[1] GoodRx.com - Lupron Depot pricing
[2] Drugs.com - Leuprolide price guide
[3] AbbVie patient assistance
[4] DrugPatentWatch.com - Lupron patents