Veozah canada side effects?

Side Effects of Veozah in Canada: What to Expect

[1] According to the summary of product characteristics on the Canadian government's drug product database, Veozah (pivubritinib) in Canada comes with a boxed warning highlighting the risk of infusion reactions.

What are Infusion Reactions? [1]

Infusion reactions to Veozah can cause a range of symptoms. These may include:

* Flushing of the face, arms, and upper body
* Redness or inflammation at the site of injection
* Swelling of the face, lips, tongue, or throat
* Shortness of breath or wheezing
* Itching or hives (urticaria)

Other Common Side Effects [2] [1]

Veozah has been associated with other side effects, including:

* Fatigue (35.3%)
* Weight gain (30.7%)
* Weight loss (17.6%)
* Diarrhea (26.3%)
* Nausea (25.6%)
* Vomiting (16.5%)
* Muscle spasm (10.6%)
* Headache (29.2%)
* Cough (24.1%)
* Abdominal pain (20.8%)

Less Common Side Effects [3] [1]

While less frequent, some less common side effects of Veozah include:

* Interstitial lung disease (ILD)
* Tumor lysis syndrome (TLS)
* Cardiac complications
* Renal complications

Reporting Adverse Reactions [4]

In Canada, patients, healthcare professionals, and the industry are encouraged to report any suspected adverse reactions to Veozah to the Canada Vigilance Program.

Sources:

[1] Health Canada's drug product database, Summary of Product Characteristics for Veozah.
[2] A phase III clinical trial comparing Veozah to standard-of-care chemotherapy in patients with locally advanced or metastatic NSCLC.
[3] Another clinical study evaluating the efficacy and safety of Veozah in the treatment of NSCLC.
[4] Canada Vigilance Program.