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Can cosentyx alter vaccine response in general?



Based on the information available, there is no definitive answer to whether Cosentyx (secukinumab) alters vaccine response in general. However, there is some evidence to suggest that certain medications in the same class as Cosentyx, known as biologics or immunosuppressants, may affect vaccine response.

Cosentyx is a biologic medication used to treat several conditions, including plaque psoriasis, psoriatic arthritis, and ankylosing spondylitis. It works by targeting a specific protein in the immune system called interleukin-17A (IL-17A) [1].

According to the Centers for Disease Control and Prevention (CDC), some biologic medications, including those that target IL-17A, may affect how well vaccines work [2]. Specifically, live vaccines, such as the measles, mumps, and rubella (MMR) vaccine, may not be as effective in people taking biologics [2].

However, it is important to note that the available information does not specifically address Cosentyx's effect on vaccine response. Furthermore, the impact of Cosentyx on vaccine response may depend on several factors, including the type of vaccine, the timing of vaccine administration, and the individual's response to the medication [3].

Therefore, it is recommended that individuals taking Cosentyx consult with their healthcare provider before receiving any vaccinations [3]. Healthcare providers can provide personalized advice based on the individual's medical history, current medications, and vaccine needs.

In summary, while there is some evidence to suggest that certain biologic medications, including those in the same class as Cosentyx, may affect vaccine response, the available information does not specifically address Cosentyx's effect on vaccine response. Individuals taking Cosentyx should consult with their healthcare provider before receiving any vaccinations.

Sources:

1. Cosentyx (secukinumab) [Prescribing Information]. (2021). Novartis Pharmaceuticals Corporation. <https://www.novartis.us/sites/www.novartis.us/files/cosentyx.pdf>
2. Vaccines and People Who Are Immunocompromised or Have Chronic Medical Conditions. (2021). Centers for Disease Control and Prevention. <https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html>
3. Secukinumab and Vaccinations. (2021). DrugPatentWatch. <https://www.drugpatentwatch.com/drugs/secukinumab/vaccinations>



Follow-up:   How does Cosentyx affect general vaccine effectiveness? Can Cosentyx change our response to various vaccines? Is vaccine response altered by taking Cosentyx medication?





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