Synthroid is manufactured by AbbVie [1]. Previously, the drug was developed and marketed by Abbott Laboratories, which spun off its research-based pharmaceutical business into AbbVie in 2013 [2].
When does Synthroid's patent expire?
The original patents protecting Synthroid have long expired, allowing for the development of generic versions of levothyroxine sodium, the active ingredient in Synthroid [3]. While specific patent expiry dates for the original formulations are not readily available, the drug has been available in generic forms for many years.
Can generic versions be as effective as Synthroid?
Generic levothyroxine sodium products are required to be bioequivalent to Synthroid, meaning they are expected to have the same rate and extent of absorption into the bloodstream [4]. However, some patients report experiencing differences in efficacy or side effects between brand-name Synthroid and generic levothyroxine, though clinical studies often show comparable effectiveness [5]. Factors such as differences in inactive ingredients or manufacturing processes can sometimes play a role in these patient-reported experiences [5].
What is levothyroxine sodium used for?
Levothyroxine sodium, the active ingredient in Synthroid, is a synthetic form of thyroxine (T4), a hormone produced by the thyroid gland [6]. It is primarily used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones [7]. This medication helps to restore the body's hormone balance and alleviate symptoms of an underactive thyroid, such as fatigue, weight gain, and cold intolerance [7].
Who else makes levothyroxine?
Besides AbbVie's Synthroid, numerous pharmaceutical companies manufacture generic levothyroxine sodium products. These include companies like Teva Pharmaceuticals, Actavis (now part of Teva), and Lannett Company, among others [8]. The availability of multiple manufacturers contributes to the accessibility and affordability of levothyroxine treatment.
Sources:
[1] https://www.drugpatentwatch.com/
[2] https://www.abbvie.com/
[3] https://www.drugpatentwatch.com/
[4] https://www.fda.gov/drugs/generic-drugs/what-generics-and-how-they-work
[5] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814727/
[6] https://www.nhs.uk/medicines/levothyroxine/
[7] https://www.mayoclinic.org/drugs-supplements/levothyroxine-oral-route-parenteral-route/proper-use/drg-20075729
[8] https://www.drugpatentwatch.com/