Lacosamide is an antiepileptic drug that is used to treat partial-onset seizures in adults and children over the age of four. It is available in oral tablet, oral solution, and injection formulations [3]. The oral tablet and solution formulations are taken by mouth, usually twice a day, with or without food. The recommended starting dose for adults is 50 mg twice daily, which can be increased to a maximum dose of 400 mg per day, depending on the patient's response and tolerance [3]. For children, the dosage is based on their weight and age [3].
Lacosamide is also available in an intravenous (IV) formulation, which is administered in a hospital or clinic setting under the supervision of a healthcare professional [2]. The IV formulation is used to treat partial-onset seizures when oral administration is not feasible or desirable, or when a rapid onset of action is required [2]. The recommended starting dose for adults is 200-400 mg per day, which is administered in two divided doses [2]. The dosage for children is based on their weight and age [2].
In conclusion, lacosamide is available in oral tablet, oral solution, and injection formulations. The oral formulations are taken by mouth, usually twice a day, with or without food. The IV formulation is administered in a hospital or clinic setting under the supervision of a healthcare professional. The dosage for both the oral and IV formulations depends on the patient's age, weight, response, and tolerance.
Sources:
[2] Vimpat (lacosamide) injection, solution. Medscape. Retrieved from https://reference.medscape.com/drug/vimpat-motpoly-xr-lacosamide-343026
[3] Vimpat (lacosamide) oral solution, tablets. DrugPatentWatch. Retrieved from https://www.drugpatentwatch.com/p/tradename/LACOSAMIDE
[4] Brodie, M. J., & Perucca, E. (2018). Lacosamide as adjunctive therapy for partial-onset seizures: Mechanisms of action, pharmacology, effects, and safety. Therapeutic advances in neurological disorders, 11, 1756285618769765. https://doi.org/10.1177/1756285618769765