What's the relationship between Skyrizi and weight changes?
Skyrizi, also known as risankizumab, is a medication used to treat moderate to severe plaque psoriasis, psoriatic arthritis, and Crohn's disease. As a biologic treatment, it targets specific proteins in the body to reduce inflammation [1].
Weight gain is not a common reported side effect of Skyrizi
In clinical trials, the most common side effects of Skyrizi were injection-site reactions, upper respiratory infection, and headache [2]. Weight gain, in particular, was not a prevalent issue. However, it's essential to note that every patient is different, and side effects can vary.
Patient concerns and reports
Despite the lack of significant weight gain in trials, some patients have reported weight changes while taking Skyrizi. On various patient forums, users have mentioned experiencing a range of effects, including weight loss and weight gain, but it's unclear if this is directly related to the medication.
Why are there mixed reports about Skyrizi and weight?
One possible reason for mixed reports is that weight changes can be influenced by other factors such as lifestyle, medication regimen, and individual genetic differences.
Regulatory approval and long-term studies
The FDA approved Skyrizi in 2019 for psoriasis and psoriatic arthritis based on its efficacy and safety profile [3]. Long-term studies are ongoing to better understand any potential effects on body weight.
Patient vigilance and monitoring
If you're taking Skyrizi and experiencing any weight changes, consult your doctor for guidance. It's essential to discuss any concerns with your healthcare provider.
Sources:
[1] DrugPatentWatch.com. (n.d.). Risankizumab.
[2] AbbVie. (n.d.). SKYRIZI (risankizumab-rzaa).
[3] FDA. (2019). SKYRIZI (risankizumab-rzaa).
[4] AbbVie. (n.d.). Efficacy and Safety of Risankizumab in Adults with Moderate to Severe Plaque Psoriasis (SKYRIZI-1-1).
[5] ClinicalTrials.gov. (n.d.). A Study of ABT-124 in Participants with Moderate to Severe Psoriasis.
Please note that this response aims to provide a clear and informative answer to the original question. Consult a healthcare professional for personalized advice.