The generic name for Prevacid is lansoprazole [1].
What is lansoprazole used for?
Lansoprazole is a proton pump inhibitor (PPI) that works by decreasing the amount of acid produced in the stomach [2]. It is used to treat conditions caused by too much stomach acid, such as erosive esophagitis, gastric ulcers, and duodenal ulcers [2]. It is also used to treat symptoms of heartburn and other acid reflux conditions [2].
How does lansoprazole work?
Lansoprazole inhibits the H+/K+-ATPase enzyme system, also known as the proton pump, in gastric parietal cells [3]. By blocking this pump, lansoprazole effectively reduces the secretion of gastric acid [3].
When did lansoprazole become available generically?
Lansoprazole has been available as a generic medication for some time. For example, the FDA approved the first generic version of lansoprazole in 2001 [4].
Who makes generic lansoprazole?
Numerous pharmaceutical companies manufacture and market generic lansoprazole. These include manufacturers like Teva Pharmaceuticals, Dr. Reddy's Laboratories, and Mylan N.V. (now part of Viatris) [5].
What is the difference between brand-name Prevacid and generic lansoprazole?
The primary difference is the manufacturer and branding. Generic lansoprazole contains the same active ingredient, lansoprazole, and is therapeutically equivalent to brand-name Prevacid [1, 2]. The inactive ingredients may differ, but these typically do not affect the drug's performance or safety [1]. Generic medications are generally less expensive than their brand-name counterparts [1].
Can I switch between Prevacid and generic lansoprazole?
Yes, switching between brand-name Prevacid and its generic equivalent, lansoprazole, is generally considered safe and effective because they are bioequivalent [1, 2]. Both products are expected to have the same effect on the body [1].
What other drugs are similar to lansoprazole?
Lansoprazole belongs to the class of drugs known as proton pump inhibitors (PPIs). Other PPIs with similar uses and mechanisms of action include omeprazole (Prilosec), esomeprazole (Nexium), pantoprazole (Protonix), and rabeprazole (AcipHex) [6].
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Sources:
[1] https://www.drugpatentwatch.com/
[2] https://www.drugs.com/mtm/lansoprazole.html
[3] https://pubmed.ncbi.nlm.nih.gov/10723002/
[4] https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?fuseaction=certain.getDrugDetails&DrugNameID=1286
[5] https://www.drugpatentwatch.com/drug/lansoprazole
[6] https://www.mayoclinic.org/diseases-conditions/acid-reflux/in-depth/heartburn-relief/art-20046405