Based on the available information, there is no direct impact of antacids on the recommended dose of tigecycline. Tigecycline is an antibiotic used to treat various bacterial infections, and its absorption is not affected by pH changes in the stomach [1][2]. Therefore, antacids, which are used to neutralize stomach acid, do not impact tigecycline's absorption.

However, it is important to note that tigecycline has a unique dosing regimen, and its use should be guided by the prescribing information [1]. The drug's absorption is relatively low and variable, and it is not significantly affected by food [2].

In summary, antacids do not have a direct impact on the recommended dose of tigecycline. However, as with any medication, tigecycline should be used according to the prescribing information, and any concerns or questions should be directed to a healthcare professional.

Sources:
[1] <https://www.drugpatentwatch.com/p/tradename/TIGECYCLINE>
[2] <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707899/>
[3] <https://pubmed.ncbi.nlm.nih.gov/946598/>