Does Humira Need Refrigeration?
Humira (adalimumab) must be refrigerated at 36°F to 46°F (2°C to 8°C) before first use to maintain stability.[1] Remove it from the fridge 15-30 minutes before injecting to reach room temperature, which reduces injection-site discomfort.
What If It's Left Out of the Fridge?
Unrefrigerated Humira is stable for up to 30 days at temperatures up to 77°F (25°C), as long as it's protected from light.[1] Discard if exposed to higher heat, frozen, or past this window. Travel packs like Humira Citrate-Free Pen allow room-temperature storage for 30 days after first use.
How to Store Humira Pens or Syringes?
Keep in the original carton in the fridge until the first dose. After first use, either refrigerate or store at room temperature (up to 77°F) for the remaining doses, not exceeding 30 days total.[1] Avoid shaking, freezing, or direct sunlight. For air travel, pack in carry-on with cooling accessories.
Why Does Humira Require Cold Storage?
As a biologic protein, Humira degrades faster at warmer temperatures, losing potency. Manufacturer guidelines ensure efficacy for treating conditions like rheumatoid arthritis, psoriasis, and Crohn's disease.[1]
Patient Tips for Travel or Power Outages?
Use cooler bags with ice packs for trips; don't let it freeze. During outages, prioritize room-temperature stability window. Check with AbbVie (1-800-633-9110) or pharmacist for batch-specific advice.[1]
[1]: Humira Prescribing Information and Storage Guidelines
[2]: FDA Label for Humira (adalimumab)