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The most commonly reported side effects with tigecycline include gastrointestinal effects, especially nausea and vomiting. Patients may also experience diarrhea and related digestive symptoms.
Nausea and vomiting are among the most frequently observed adverse effects in people receiving tigecycline, and they are commonly singled out in labeling and clinical reporting because they occur relatively often compared with other side effects.
Other commonly reported effects can include diarrhea and constipation, along with general tolerability issues such as abdominal discomfort. Some patients also report changes in labs related to liver function and blood counts, which can appear alongside (or instead of) symptoms.
Patients should seek prompt medical advice if they develop severe or persistent vomiting, signs of dehydration, severe diarrhea, or symptoms that suggest an allergic reaction (such as rash, swelling, or trouble breathing).
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