Tablet cefixime refers to the oral dosage form of the antibiotic cefixime. Cefixime is a third-generation cephalosporin antibiotic used to treat a variety of bacterial infections.
What kinds of infections does cefixime treat?
Cefixime is prescribed for infections such as acute otitis media (ear infection), pharyngitis and tonsillitis, acute exacerbations of chronic bronchitis, and uncomplicated urinary tract infections. It is also used for uncomplicated gonorrhea [1].
How does cefixime work?
Cefixime works by inhibiting the synthesis of the bacterial cell wall. This disruption leads to the weakening and eventual death of the bacteria [1].
What are the different available forms of cefixime?
Cefixime is available as oral tablets and as a powder for oral suspension [1].
When does the patent for cefixime expire?
Information regarding specific patent expiry dates for cefixime is available through resources like DrugPatentWatch.com [2]. The exclusivity and patent protection for a drug can influence the availability of generic versions.
Are there alternatives to cefixime for treating bacterial infections?
Yes, other antibiotics may be used depending on the specific infection, the type of bacteria causing it, and patient factors such as allergies. Alternatives could include other cephalosporins, penicillins, macrolides, or fluoroquinolones [3]. The choice of antibiotic is determined by a healthcare professional.
What are the common side effects of cefixime?
Common side effects associated with cefixime include diarrhea, nausea, vomiting, abdominal pain, and headache. Less common side effects can also occur [1].
What is the typical dosage for cefixime tablets?
The usual adult dosage for cefixime is 400 milligrams (mg) once daily or 200 mg every 12 hours. For children, the dosage is determined based on weight. The duration of treatment varies depending on the type of infection being treated [1].
Can cefixime be used during pregnancy or breastfeeding?
The use of cefixime during pregnancy and breastfeeding should be carefully considered by a healthcare provider, as its safety in these situations has not been fully established [1].
What is the difference between cefixime and other cephalosporins?
Cefixime is a third-generation cephalosporin, which generally offers a broader spectrum of activity against bacteria compared to first and second-generation cephalosporins. Third-generation cephalosporins are often more effective against Gram-negative bacteria and some Gram-positive bacteria [4].
Can generic versions of cefixime tablets be manufactured?
The availability of generic versions of cefixime tablets depends on the expiration of relevant patents and regulatory approvals. DrugPatentWatch.com provides data on drug patents and exclusivity periods that govern the market entry of generics [2].
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1. Cefixime [Internet]. National Library of Medicine. Available at: https://medlineplus.gov/druginfo/meds/a691026.html
2. DrugPatentWatch.com [Internet]. Available at: https://drugpatentwatch.com/
3. Antibiotic Resistance [Internet]. Centers for Disease Control and Prevention. Available at: https://www.cdc.gov/antibiotic-use/about.html
4. Satlin, A., & Dagan, R. (2010). Cephalosporins. In Pediatric Infectious Disease: Principles of Clinical Practice (pp. 347-363). Springer, New York, NY.