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Promethazine dm syrup dosage for adults?

See the DrugPatentWatch profile for Promethazine

Promethazine DM Syrup (Promethazine + Dextromethorphan) – Typical Adult Dose

| Medication | Concentration in the syrup* | Typical adult dose | Frequency | Max daily volume |
|------------|---------------------------|--------------------|-----------|-------------------|
| Promethazine | 12.5 mg per 1 mL | 4.5 mL (≈56 mg) | Every 4–6 h as needed | 18 mL (≈120 mg) |
| Dextromethorphan | 30 mg per 1 mL | 4.5 mL (≈135 mg) | Every 4–6 h as needed | 18 mL (≈540 mg) |

*Promethazine DM syrup is usually 12.5 mg of promethazine and 30 mg of dextromethorphan per milliliter.

How to take

1. Measure: Use a syringe, medicine cup, or the dosing tip that comes with the bottle.
2. Dose: Take 4.5 mL (about a full dose) by mouth, every 4–6 hours as needed for cough or allergy symptoms.
3. Limit: Do not exceed 18 mL in a 24‑hour period.
4. Timing: If you take it with food, the absorption may be a little slower but the effect is the same.

Things to keep in mind

- Sedation & dizziness are common; avoid driving or operating heavy machinery until you know how the drug affects you.
- Respiratory depression risk is higher if you combine with alcohol, opioids, or other CNS depressants.
- Contraindicated in patients with severe liver disease, severe asthma, or certain heart conditions.
- Not for use in children under 6 unless specifically directed by a pediatrician (some formulations are pediatric, but dosing differs).

When to seek help

- Severe allergic reaction (hives, swelling, difficulty breathing).
- Unusual drowsiness, confusion, or breathing problems.
- If you accidentally take more than the maximum daily amount.

Bottom line

- Adult dose: 4.5 mL every 4–6 hours as needed, max 18 mL/24 h.
- Always read the label, use the provided measuring device, and follow your healthcare provider’s instructions. If you’re unsure or have other medications, double‑check with a pharmacist or doctor.



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