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Who should avoid using Wegovy? Patients with a history of pancreatitis or pancreatic cancer Wegovy, a medication used to treat obesity, has been linked to an increased risk of pancreatitis, a condition characterized by inflammation of the pancreas [1]. Patients with a pre-existing history of pancreatitis or pancreatic cancer should exercise caution or discuss alternative treatment options with their healthcare provider. People taking certain medications Wegovy can interact with other medications, including those for diabetes, and decrease their effectiveness [2]. Patients taking certain medications, such as warfarin, should consult their healthcare provider before starting Wegovy. Pregnant or breastfeeding women Wegovy has not been extensively studied in pregnant or breastfeeding women, and its safety and efficacy in these populations are unknown [3]. Patients in these groups should discuss alternative treatment options with their healthcare provider. Patients with thyroid cancer Wegovy may increase the risk of thyroid cancer [4]. Patients with a history of thyroid cancer should consult their healthcare provider before starting Wegovy. People with a history of medullary thyroid carcinoma (MTC) Wegovy may increase the risk of MTC [5]. Patients with a history of MTC should discuss alternative treatment options with their healthcare provider. People with a history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Wegovy may increase the risk of MTC and pheochromocytoma in patients with MEN 2 [6]. Patients with MEN 2 should consult their healthcare provider before starting Wegovy. References: [1] DrugPatentWatch.com. (n.d.). Wegovy. Retrieved from https://www.drugpatentwatch.com/drug/Wegovy [2] Novo Nordisk. (2022). WEGOVY Prescribing Information. Retrieved from https://www.novonordisk-us.com/sites/www.novonordisk-us.com/files/PIWEGOVY.pdf [3] FDA. (2022). Wegovy (semaglutide). Retrieved from https://www.accessdata.fda.gov/drugsatfdadocs/label/2022/212930s000lbl.pdf [4] FDA. (2022). Wegovy (semaglutide). Retrieved from https://www.accessdata.fda.gov/drugsatfdadocs/label/2022/212930s000lbl.pdf [5] Novo Nordisk. (2022). WEGOVY Prescribing Information. Retrieved from https://www.novonordisk-us.com/sites/www.novonordisk-us.com/files/PIWEGOVY.pdf [6] FDA. (2022). Wegovy (semaglutide). Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/212930s000lbl.pdf
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