Mupirocin is used to treat impetigo, a common skin infection that causes red sores that quickly rupture, ooze, and then form a yellowish-brown crust [1]. It is also prescribed for certain other skin infections caused by bacteria [1].
How does mupirocin work to treat infections?
Mupirocin is an antibiotic that works by inhibiting bacterial protein synthesis [2]. It targets an enzyme called isoleucyl-tRNA synthetase, which is essential for bacteria to produce proteins [2]. By blocking this enzyme, mupirocin prevents the bacteria from growing and multiplying, allowing the body's immune system to clear the infection [2].
Are there different forms of mupirocin available?
Mupirocin is available as a topical ointment and a nasal ointment [1]. The ointment form is typically applied directly to the affected skin areas [1]. The nasal ointment is used to eliminate bacteria from the nose, particularly in individuals who are carriers of Staphylococcus aureus, to prevent the spread of infection [3].
What are the common side effects of mupirocin?
Common side effects of topical mupirocin include local reactions at the application site, such as burning, stinging, itching, redness, and dryness [1]. These side effects are usually mild and temporary [1].
Can mupirocin be used for other types of infections?
While mupirocin is primarily used for bacterial skin infections like impetigo, its effectiveness is limited to specific types of bacteria [1]. It is not effective against viral or fungal infections [1]. Doctors prescribe mupirocin based on the specific bacteria suspected or confirmed to be causing the infection [1].
When does mupirocin treatment usually end?
Treatment duration with mupirocin varies depending on the condition being treated and the doctor's assessment. For impetigo, treatment typically lasts for a week to ten days [1]. It is important to complete the full course of treatment as prescribed by a healthcare professional, even if symptoms improve sooner, to ensure the infection is fully eradicated and to prevent the development of antibiotic resistance [1].