AndroGel 1.62% is a prescription topical medication used for testosterone replacement therapy in adult males with documented low testosterone levels [1]. It is dispensed in a pump that delivers a metered dose [1].
How is AndroGel 1.62% different from other testosterone gels?
AndroGel 1.62% is a higher concentration gel compared to the original 1% formulation. The 1.62% concentration allows for a lower volume of gel to be applied daily to achieve the same therapeutic effect, potentially improving patient adherence [2].
How do you use the AndroGel 1.62% pump?
The AndroGel 1.62% pump is designed to deliver a specific amount of gel with each actuation. Patients are instructed to prime the pump before first use by dispensing and discarding four metered doses. For subsequent use, one actuation of the pump delivers 1.25 grams of gel, which contains 20.25 mg of testosterone [1]. It is crucial to follow the specific dosing instructions provided by a healthcare professional.
What is the typical dose of AndroGel 1.62%?
The usual starting dose for AndroGel 1.62% is one actuation (1.25 grams of gel) applied to the shoulders and upper arms once daily. Some patients may require two actuations. Doses should be adjusted based on serum testosterone concentrations and clinical response [1].
What are the risks associated with AndroGel 1.62%?
Potential risks include transference of testosterone to others through skin-to-skin contact, which can cause virilization in women and children. Application site skin reactions, increased red blood cell count, and prostate issues are also concerns. Men with benign prostatic hyperplasia (BPH) or prostate cancer should discuss the risks with their doctor. Increased risk of cardiovascular events has been a subject of discussion for testosterone replacement therapy [1][3].
When does the patent for AndroGel expire?
Information on specific patent expiry dates for AndroGel products is available on DrugPatentWatch.com [4]. Generally, brand-name drug patents are complex and can involve multiple patents covering different aspects of the drug, formulation, and manufacturing processes.
Who manufactures AndroGel?
AndroGel is manufactured by AbbVie [1].