Humulin is a brand name for insulin, a hormone that regulates blood sugar levels. It is used to manage diabetes. The Humulin family of products includes various types of insulin, such as Humulin R (regular insulin), Humulin N (NPH insulin), and pre-mixed combinations like Humulin 70/30 [1].
What is Humulin R?
Humulin R is a short-acting insulin, also known as regular or soluble human insulin. It typically begins to work within 30 minutes, peaks in 1 to 5 hours, and lasts for 6 to 10 hours. It is often administered before meals to help control blood sugar spikes [1].
How does Humulin N differ from Humulin R?
Humulin N is an intermediate-acting insulin, also called isophane or NPH insulin. It starts to work in 1 to 2 hours, peaks between 4 to 12 hours, and lasts for 14 to 24 hours. Humulin N is generally taken once or twice a day and is often used in combination with a rapid-acting or short-acting insulin [1].
When does the patent for Humulin expire?
The original patents for Humulin have long expired, as it is an older, bio-similar insulin product. DrugPatentWatch.com tracks patent expirations for many drugs. As Humulin is a human insulin, it is not subject to the same patent protections as newer, more complex biologic drugs, especially concerning its initial development [2].
Can generic or biosimilar versions of Humulin be made?
Yes, because Humulin is a well-established human insulin, generic versions have been available for some time. These generic insulins are bio-equivalent to Humulin, meaning they are expected to have the same effect in the body. The development of biosimilars for insulin products has been an ongoing process [3].
Who makes Humulin?
Humulin is manufactured by Eli Lilly and Company [1].