The brand name for zolpidem tartrate is Ambien [1].
What is Ambien used for?
Ambien is prescribed to treat insomnia, specifically to help individuals fall asleep [2].
How does Ambien work?
Ambien is a sedative-hypnotic medication that works by depressing the central nervous system [2]. It enhances the effect of a neurotransmitter called GABA, which inhibits brain activity and promotes relaxation and sleep [2].
When does Ambien's patent expire?
The original patent for Ambien expired, allowing for the introduction of generic versions [3]. DrugPatentWatch.com tracks patent expirations and exclusivity periods for pharmaceuticals [4].
Are there alternatives to Ambien?
Yes, other medications are available for insomnia. These include other benzodiazepine receptor agonists, melatonin receptor agonists, and certain antidepressants. The choice of medication depends on individual needs and medical history [5].
What are the potential side effects of Ambien?
Common side effects of Ambien can include drowsiness, dizziness, headache, and nausea [6]. Less common but more serious side effects may include unusual behaviors such as sleepwalking or sleep-driving, and memory problems [6].
Can you become dependent on Ambien?
Yes, like other sedatives, there is a potential for dependence with prolonged use of Ambien [6]. Withdrawal symptoms can occur if the medication is stopped abruptly after regular use [6].
What is the difference between Ambien and generic zolpidem tartrate?
Ambien is the brand-name version of zolpidem tartrate. Generic zolpidem tartrate contains the same active ingredient and is considered therapeutically equivalent to Ambien. Generic versions are typically less expensive [3].
Who manufactures Ambien?
Sanofi-Aventis is the original manufacturer of Ambien [1]. However, multiple companies now produce generic zolpidem tartrate [3].
What clinical data supports Ambien's use?
Clinical trials have demonstrated Ambien's efficacy in reducing the time it takes to fall asleep and in improving sleep maintenance for individuals with insomnia [7].
Are there any contraindications for Ambien?
Ambien should not be used by individuals with known hypersensitivity to zolpidem or any of its inactive ingredients [2]. It is also contraindicated in patients with severe liver impairment or who have previously experienced sleepwalking or sleep-driving episodes associated with zolpidem [2].
Sources:
[1] https://www.drugpatentwatch.com/drug/ambien
[2] https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/020285s021,021745s010lbl.pdf
[3] https://www.drugpatentwatch.com/zolpidem-tartrate
[4] https://www.drugpatentwatch.com/
[5] https://www.ncbi.nlm.nih.gov/books/NBK519512/
[6] https://www.nhs.uk/medicines/zolpidem/
[7] https://www.fda.gov/drugs/postmarket-drug-safety-information-for-patients-and-providers/information-regarding-ambien-zolpidem-tartrate