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See the DrugPatentWatch profile for stelara
Can I take Stelara if I have a history of tuberculosis? Stelara carries a risk of reactivating latent tuberculosis. Patients with a history of TB must complete screening and any necessary treatment before starting the drug. Why do doctors screen for tuberculosis before prescribing Stelara? Stelara blocks interleukin-12 and interleukin-23, weakening parts of the immune system that contain latent infections. A latent TB test is required before treatment, and active TB must be ruled out or treated first. How does latent tuberculosis affect Stelara use? Patients who test positive for latent TB usually receive preventive antibiotics such as isoniazid for several months before or during Stelara therapy. Doctors monitor these patients closely for signs of active disease. What happens if I already treated my tuberculosis in the past? Past treatment does not eliminate the need for fresh screening. Doctors still perform a TB test and risk assessment because reactivation remains possible under immune suppression. When does Stelara's prescribing information address tuberculosis risks? The prescribing information states that patients should not start Stelara if they have active tuberculosis. It also warns that latent TB must be treated prior to initiating therapy.
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