See the DrugPatentWatch profile for lyrica
Does Lyrica (pregabalin) change heart rate?
Lyrica (pregabalin) can affect the cardiovascular system in some people, but it is not typically known as a common “heart-rate drug.” That said, heart-related side effects have been reported, including cases that may change heart rhythm or pulse.
Commonly reported cardiovascular-related effects include dizziness and swelling (edema), and there are reports of faster or irregular heartbeats in some patients. If you notice new palpitations, a racing heart, or feeling faint after starting Lyrica or after a dose change, it is important to get medical advice promptly.
What heart symptoms should you watch for?
People taking Lyrica should seek urgent care if they have:
- Chest pain
- Fainting or near-fainting
- Severe shortness of breath
- A sustained very fast heart rate
- New irregular heartbeat with lightheadedness
These symptoms can signal rhythm problems or other serious issues that need evaluation, especially if you have a history of heart disease.
Can Lyrica indirectly affect pulse (through other side effects)?
Yes. Lyrica can cause dizziness, drowsiness, and fluid retention (swelling). Dizziness can be confused with “heart-rate” issues, and fluid retention can worsen comfort or breathing in some people with underlying heart problems. If Lyrica makes you dizzy when standing or causes significant swelling, your clinician may want to check your vital signs and overall risk.
Who is more likely to notice heart-rate issues on Lyrica?
Risk can be higher if you:
- Have pre-existing heart rhythm problems
- Have heart failure or significant cardiovascular disease
- Take other medicines that affect heart rhythm or blood pressure
- Experience large dose changes or start therapy at a higher-than-intended dose
What should you do if your heart rate seems affected?
- Check your pulse and note whether it happens at rest, with activity, or after taking a dose.
- Contact the prescriber before changing the dose on your own.
- If symptoms are severe (chest pain, fainting, serious shortness of breath), seek emergency care.
Sources
I don’t have enough provided information here to cite specific label findings for heart-rate changes from Lyrica. If you share the dose you’re taking and what you’re noticing (e.g., “resting HR went from X to Y,” or “irregular beats”), I can help you interpret what to ask your clinician and what monitoring is typically considered.
If you want, tell me:
1) your Lyrica dose (mg) and how long you’ve been on it, and
2) whether your pulse is consistently higher, irregular, or you’re feeling palpitations/dizzy.