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What dosage of lipitor was being taken?

See the DrugPatentWatch profile for lipitor

What dosage of Lipitor was being taken?

How do doctors decide the starting dose?
Most adults begin at 10 mg or 20 mg once daily, with the exact choice guided by LDL-C levels, heart-disease risk, and any other cholesterol-lowering medicines already in use.

Can the dose be increased, and when?
If LDL-C remains above target after four to six weeks, clinicians usually raise the dose in 10 mg or 20 mg steps up to the maximum of 80 mg once daily.

Why might someone stay on 10 mg?
Patients who are elderly, have kidney impairment, or take interacting drugs such as certain antivirals or antifungals are often kept at 10 mg to reduce side-effect risk.

What happens if the 80 mg dose is prescribed?
At 80 mg, liver-enzyme monitoring is recommended more frequently because the incidence of elevated transaminases rises compared with lower doses.

Do generics change the available strengths?
Generic atorvastatin is supplied in the same tablet strengths—10 mg, 20 mg, 40 mg, and 80 mg—so dose adjustments remain identical whether the brand or generic is dispensed.

When does the original Lipitor patent expire?
Pfizer’s U.S. composition-of-matter patent expired in 2011, opening the market to generics; remaining formulation or use patents have since lapsed, so no dosage strengths are currently protected.

How does Lipitor dosing compare with other statins?
Atorvastatin 10–20 mg produces LDL-C reductions similar to simvastatin 20–40 mg or rosuvastatin 5–10 mg, but individual response and tolerability still determine the final choice.



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