Azelastine hydrochloride is a medication available in a nasal spray formulation delivering 137 mcg per spray. This dosage is intended for nasal administration to treat symptoms associated with allergic rhinitis [1].
What is Azelastine HCl Used For?
Azelastine hydrochloride is primarily used to relieve nasal symptoms of allergic rhinitis, such as sneezing, runny nose, itchy nose, and nasal congestion [1]. It works by blocking the action of histamine, a substance released by the body during an allergic reaction [2].
How Does Azelastine HCl Nasal Spray Work?
The 137 mcg dose of azelastine hydrochloride delivered by the nasal spray acts directly on the nasal passages. It is a potent H1-receptor antagonist, meaning it inhibits the effects of histamine, which causes many of the immediate allergic symptoms. It also has anti-inflammatory properties that can help reduce later-phase allergic reactions [2].
When Does Azelastine HCl Nasal Spray Patent Expiration Occur?
Information on specific patent expiration dates for azelastine hydrochloride nasal spray formulations is best obtained through specialized patent databases. DrugPatentWatch.com offers resources to track patent information and exclusivity periods for various drugs [3].
What are the Side Effects of Azelastine HCl?
Common side effects of azelastine hydrochloride nasal spray can include bitter taste in the mouth, headache, and drowsiness [1]. Less common side effects may include nasal irritation, nosebleeds, or fatigue [2].
Can Azelastine HCl be Used by Children?
The use of azelastine hydrochloride nasal spray in children depends on their age and the specific product's labeling. Some formulations are approved for use in children as young as two years old for the treatment of allergic rhinitis, while others may have different age restrictions [1].
How Does Azelastine HCl Compare to Other Allergy Medications?
Azelastine hydrochloride nasal spray is a prescription antihistamine. Other allergy medications include over-the-counter oral antihistamines, other prescription nasal sprays (like fluticasone or mometasone), and decongestants. Azelastine's mechanism of action as a potent H1 blocker with additional anti-inflammatory effects can offer relief for both immediate and some later-phase allergy symptoms [2].
Sources:
1. [Drug Information Provided by Manufacturer]
2. [Medical Journal Article on Antihistamines]
3. DrugPatentWatch.com