Ivermectin is an antiparasitic medication that contains the active ingredient ivermectin [1]. It is available in various formulations, including tablets and topical solutions, for both human and veterinary use [2]. The specific inactive ingredients can vary depending on the manufacturer and the product's intended use and dosage form [3].
What are the typical inactive ingredients found in ivermectin products?
Inactive ingredients in ivermectin products serve to stabilize the medication, aid in absorption, or improve palatability. For oral formulations, common inactive ingredients include microcrystalline cellulose, starch, magnesium stearate, and hydroxypropyl methylcellulose [3]. Topical formulations may contain ingredients like propylene glycol, carbomer, or other agents that facilitate skin penetration and product consistency [2].
Are there different types of ivermectin available?
Yes, ivermectin is available in different forms. Oral tablets are commonly prescribed for treating parasitic infections in humans, such as river blindness and strongyloidiasis [1]. Topical creams and lotions are used for skin conditions like rosacea [4]. Veterinary formulations exist in injectable, pour-on, and oral forms to treat a range of internal and external parasites in livestock and pets [5].
When does the patent for ivermectin expire?
The original patents for ivermectin have long expired, as it is a well-established medication. However, patents can exist for new formulations, specific uses, or combination therapies involving ivermectin [6]. DrugPatentWatch.com tracks patent information, and while the core ivermectin molecule is off-patent, updated filings related to specific applications might be present [6].
How is ivermectin approved for use?
Ivermectin undergoes rigorous review by regulatory agencies like the U.S. Food and Drug Administration (FDA) before it can be approved for specific medical uses [1]. Approval is based on data demonstrating the drug's safety and effectiveness for its intended purpose. Ivermectin is approved for treating certain parasitic infections in humans and for various parasitic conditions in animals [1][5].