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Are common antacids safe to take with Lipitor? Antacids do not affect how Lipitor works or change its levels in the blood. Studies show that aluminum-magnesium hydroxide antacids produce no meaningful interaction with atorvastatin, the active ingredient in Lipitor. How do antacids affect drug absorption? Some drugs rely on stomach acid for proper absorption. Antacids raise stomach pH and can slow or block absorption of certain medications. Lipitor belongs to the group of drugs that does not require acid for proper absorption. Data from pharmacokinetic studies confirm that antacids do not alter its bioavailability. Why do doctors still recommend spacing them apart? Timing recommendations exist for man
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