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How long does an unused Cosentyx syringe stay stable at room temperature? Secukinumab, the active ingredient in Cosentyx, stays chemically stable for up to 30 days when kept at temperatures below 30°C (86°F). After 30 days outside refrigeration, the product should be discarded even if it still looks normal. How does refrigeration affect its shelf life? Cosentyx syringes and pens require constant refrigeration between 2–8°C (36–46°F). This keeps the biologic active until its printed expiration date on the carton. What happens if an unused syringe is left out overnight? Leaving a syringe out for only a few hours or overnight does not shorten its full refrigerated shelf life. It can be returned to the fridge immediately after brief excursions and still useable until the labeled expiry. How are patients told to store Cosentyx before injection? The prescribing information directs patients to keep syringes and pens in the original carton to protect from light and to avoid freezing. Freezing damages the protein structure and makes the syringe unusable.
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